Annual Gene Therapy Symposium for
Heart, Lung, and Blood Diseases
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UC Davis

 


6th Annual Gene Therapy Symposium for Heart, Lung, and Blood Diseases
Focus Topic: RNAi and Therapeutic Targeting
November 14-16, 2007 - Sonoma, California

Program

 
 

Wednesday, November 14, 2007 - Welcoming Reception

  

Judy LiebermanThursday, November 15, 2007

Keynote Speaker

  • Judy Lieberman, M.D. Ph.D. (Harvard University)
    “Delivering RNA Interference”

 

Session I  

  • Paula M. Cannon, Ph.D. (Childrens Hospital Los Angeles)
    “Can We Reduce the Mutagenic Potential of Integrating Vectors?”
  • Mark A. Kay, M.D., Ph.D. (Stanford University)
    “Defining the Rate-Limiting Factors for RNAi and microRNA Function in Mammals”
  • Mark E. Davis, Ph.D. (California Institute of Technology)
    “Systemic Delivery of siRNA via Targeted Nanoparticles
Student/Fellow Presentations and Poster Session - Link to Information

Session II   

  • Alfred S. Lewin, Ph.D. (University of Florida)
    “AAV-Mediated RNA Interference Leads to Improved Contractility and Calcium Handling in Cardiomyocytes”

  • Ralph A. Tripp, Ph.D. (University of Georgia)
    “RNAi and Therapeutic Targeting of Respiratory Virus Infections”
  • Bruce A. Sullenger, Ph.D. (Duke University)
    “Therapeutic Applications of Aptamers that Target Cell Surface Receptors”

“Practical Strategies”: RNAi Libraries

  • William C. Hahn, M.D., Ph.D., (Dana-Farber Cancer Institute)

   

 

 

John RossiFriday, November 16, 2007

Workshop: “The Nuts and Bolts of RNAi for Therapeutic Applications”

  • John J. Rossi, Ph.D.
    (Beckman Research Institute of the City of Hope)

Session III

  • Michael T. McManus, Ph.D. (University of California, San Francisco)
    “Mammalian RNA Interference Pathways”
  • K. Sue O'Shea, Ph.D. (University of Michigan)
    “Probing Gene Function in Development: RNAi in ES cells and Embryos”

  • Ian MacLachlan, Ph.D. (Protiva Biotherapeutics, Inc.)
    "Preclinical Pharmacology of a SNALP Delivered siRNA-based Therapy for Hypercholesterolemia"
Student/Fellow Presentations and Poster Session - Link to Information

Session IV

  • Tariq M. Rana, Ph.D. (University of Massachusetts)
    “Small RNAs: Regulators and Guardians of the Genome”

  • Kathleen M. Sakamoto, M.D., Ph.D. (University of California, Los Angeles)
    “Downregulation of CREB in Normal and Neoplastic Hematopoietic Cells”

  • Meri T. Firpo, Ph.D. (University of Minnesota)
    “Does OCT4 Regulate Self-Renewal in Adult and Embryonic Stem Cells?”


   

   

Gene Therapy Symposium 2007

 
 

Supported by the National Heart, Lung, and Blood Institute, National Institutes of Health. Additional support provided by the National Institute of Allergy and Infectious Diseases, National Institute of Biomedical Imaging and Bioengineering, NIH; Baxter BioScience, Calando Pharmaceuticals, Xenogen Corporation/Caliper Life Sciences; California National Primate Research Center; and the UC Davis Clinical and Translational Science Center.